2-AMINO-4-ACETYL-7-BROMO-8-HYDROXY-3,8-DIHYDROTHIAZOLO[5,4-b]INDOLE HYDROBROMIDE PROTECTING BODY AGAINST HYPOXIA AND LIVER AGAINST POISONING WITH CARBON TETRACHLORIDE Russian patent published in 2006 - IPC C07D513/04 A61K31/429 A61P1/16 

Abstract RU 2281949 C2

FIELD: organic chemistry, chemical technology, medicine.

SUBSTANCE: invention relates to a new 2-amino-4-acetyl-7-bromo-8b-hydroxy-3a,8b-dihydrothiazolo[5,4-b]indole hydrobromide of the formula (1) that is able to protect body against hypoxia and liver against poisoning with carbon tetrachloride. The melting point of this compound is 266-267°C (with decomposition). The compound is synthesized from 1-acetyl-5-bromo-3-indolinone and elemental bromine in dioxane medium followed by addition of thiourea in isopropyl alcohol.

EFFECT: valuable medicinal properties of compound.

2 tbl, 1 ex

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RU 2 281 949 C2

Authors

Marysheva Vera Vasil'Evna

Shabanov Petr Dmitrievich

Dates

2006-08-20Published

2004-09-21Filed