FIELD: organic chemistry. SUBSTANCE: product: 2-amino-4-acetylthiazolo-[5,4-b] -indole, m. p. is 256 C (with decomposition). Reagent 1: 1-acetyl-2-isothioureido-3-indolinone hydrobromide. Reaction conditions: cyclization in medium of diethylene glycol dimethyl ester, at 100-160 C or in medium of ethanol at 60-78 C. EFFECT: improved method of synthesis. 2 cl
| Title |
Year |
Author |
Number |
| HYDROBROMIDE OF 1-ACETYL-2-ISOTHIOUREIDO-3-INDOLINONE PROTECTED LIVER AGAINST POISONING OF CARBON TETRACHLORIDE |
1991 |
- Velezheva V.S.
- Mel'Man A.I.
- Tomchin A.B.
- Marysheva V.V.
- Smirnov A.V.
- Okovityj S.V.
- Gajvoronskaja V.V.
|
RU2009127C1 |
| 4-ACETYL-3-BENZYL-2-METHYLTHIOIMIDAZO (4,5 ) INDOLE PROTECTING LIVER AGAINST POISONING OF CARBON TETRACHLORIDE |
1991 |
- Velezheva V.S.
- Mel'Man A.I.
- Tomchin A.B.
- Okovityj S.V.
- Smirnov A.V.
- Gajvoronskaja V.V.
|
RU2009141C1 |
| N-(1-ACETYLINEDOL-3-ONE-2-YL)-THIOCARBAMIDE PROTECTING LIVER FROM TOXIC EFFECT OF CARBON TETRACHLORIDE |
1990 |
- Velezheva V.S.
- Mel'Man A.I.
- Tomchin A.V.
- Smirnov A.S.
- Gajvoronskaja V.V.
- Okovityj S.V.
|
SU1736149A1 |
| 8-AMINO-3-(2-MORPHOLINOETHYLTHIO)-1,2,4-TRIAZINO-[5,6-B]-INDOLE HYDROCHLORIDE PROTECTING LIVER AGAINST CARBON TETRACHLORIDE INTOXICATION AND PROCESS ACCELERATING AFTER PHYSICAL LOADING |
1991 |
- Tomchin A.B.
- Smirnov A.V.
- Gajvoronskaja V.V.
- Okovityj S.V.
- Spivakova R.P.
|
SU1809608A1 |
| 3-[3-(4-METHYLPIPERAZINE-1-YL)-PROPYLTHIO]-1,2,4-TRIAZINO- [5,6-B]-INDOLE HYDROCHLORIDE PROTECTING LIVER AGAINST CARBON TETRACHLORIDE INTOXICATION |
1991 |
- Tomchin A.B.
- Zhukova T.I.
- Kuznetsova T.A.
- Smirnov A.V.
- Gajvoronskaja V.V.
- Okovityj S.V.
|
SU1829358A1 |
| 2-AMINO-4-ACETYL-7-BROMO-8-HYDROXY-3,8-DIHYDROXYTIAZOLO[5,4-b]INDOLE FOR LIVER PROTECTION FROM POISONING WITH CARBON TETRACHLORIDE |
2004 |
- Marysheva Vera Vasil'Evna
- Shabanov Petr Dmitrievich
|
RU2286348C2 |
| 3-(2-DIPROPYLAMINOETHYLTHIO)-1,2,4-TRIAZINO-[5,6-B]-INDOLE HYDROCHLORIDE PROTECTING LIVER AGAINST CARBON TETRACHLORIDE INTOXICATION |
1991 |
- Tomchin A.B.
- Smirnov A.V.
- Gajvoronskaja V.V.
- Okovityj S.V.
- Nagornev S.N.
|
SU1829357A1 |
| 5-(2-MORPHOLINOETHYL)-3-PROPYLTHIO-1,2,4-TRIAZINO-[5,6-B]-INDOLE PROTECTING LIVER AGAINST CARBON TETRACHLORIDE INTOXICATION |
1989 |
- Tomchin A.B.
- Smirnov A.V.
- Gajvoronskaja V.V.
- Okovityj S.V.
- Katkov V.F.
- Nagornev S.N.
|
SU1626646A1 |
| 2-AMINO-4-ACETYL-7-BROMO-8-HYDROXY-3,8-DIHYDROTHIAZOLO[5,4-b]INDOLE HYDROBROMIDE PROTECTING BODY AGAINST HYPOXIA AND LIVER AGAINST POISONING WITH CARBON TETRACHLORIDE |
2004 |
- Marysheva Vera Vasil'Evna
- Shabanov Petr Dmitrievich
|
RU2281949C2 |
| N,N'-DI-(3-OXO-2-INDOLYL)-S-BENZYLISOTHIOUREA PROTECTING LIVER AGAINST CARBON TETRACHLORIDE INTOXICATION |
1989 |
- Tomchin A.B.
- Smirnov A.V.
- Gajvoronskaja V.V.
- Okovityj S.V.
- Katkov V.F.
|
SU1640973A1 |
