FIELD: medicine, neurooncology.
SUBSTANCE: the present innovation deals with treating patients at low-differentiated cerebral gliomas. The method deals with introduction of anti-tumor chemopreparations. So, at first, one should catheterize common carotid artery (CCA) through a surface temporal artery at the side of the tumor, moreover, the catheter should be guided 1 cm below CCA bifurcation. Out of catheterized CCA one should sample 30 ml arterial autoblood into a syringe that contains 1 ml citrate conservant; then it should be supplemented with anti-tumor chemopreparations in therapeutic dosages. The mixture obtained should be incubated in a thermostat at 37°C for 1 h and introduce under the pressure and through the catheter into a patient's CCA once for 2 h. If necessary, this procedure should be repeated in 2 mo. The innovation provides decreased sizes or the absence of further tumor growth due to creating high concentration of chemopreparations directly in the tumor while they pass hematoencephalic barrier at their introduction upon autoblood and it considerably prolongs life duration in such patients.
EFFECT: higher efficiency of therapy.
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Authors
Dates
2007-11-20—Published
2006-08-03—Filed