NOVEL METHOD FOR PREPARING IMIPENEM Russian patent published in 2008 - IPC C07D477/20

Abstract RU 2314308 C2

FIELD: organic chemistry, antibiotics, chemical technology.

SUBSTANCE: invention relates to compound of the formula (I) wherein R₁ represents p-nitrobenzyl or p-methoxybenzyl group; R₂ and R₃ can be similar or different, and each represents independently (C₁-C₆)-alkyl or aryl group, or its derivative. Also, invention relates to a method for synthesis of compound of the formula (I). Except for, invention describes a method for synthesis of imipenem of the formula (II) using the compound of the formula (I).

EFFECT: improved method of synthesis.

9 cl, 5 tbl, 3 ex

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RU 2 314 308 C2

Authors

Bae Khiun Seop

Khvang Tae Seop

Akhn Chan Jong

Okh Chang Khoon

Kim Moo Sung

Dates

2008-01-10—Published

2004-12-09—Filed