PHENYLACETIC ACID SUBSTITUTED ESTERS AS SHORT-ACTING SEDATIVE SOPOROFIC AGENTS FOR SHORT-TERM ANESTHESIA AND PROVIDING SEDATIVE EFFECT, INTERMEDIATE COMPOUND, PHARMACEUTICAL COMPOSITION AND USING Russian patent published in 2008 - IPC C07C235/20 C07C69/736 A61K31/216 A61P23/00 

FIELD: organic chemistry, medicine, pharmacy.

SUBSTANCE: invention relates to compound of the formula (I):

wherein R¹ represents (C₂-C₆)-alkyl; each radical among R², R³ and R⁴ represents (C₁-C₆)-alkyl under condition that sum of carbon atoms in R¹, R², R³ and R⁴ is above 7. Also, invention relates to compound of the formula (II):

wherein R¹ represents ethyl; R⁴ represents propyl; R⁵ represents hydrogen atom. Also, invention relates to a pharmaceutical composition possessing capacity for providing and maintaining anesthesia or sedative effect and comprising the effective dose of compound of the formula (I) and a pharmaceutically acceptable carrier. Also, invention relates to using compound of the formula (I) for preparing a medicinal agent used for providing and maintaining anesthesia or sedative effect in mammal, and to a method for providing or maintaining anesthesia wherein indicated method involves administration the therapeutically effective dose of compound of the formula (I) to a mammal.

EFFECT: improved and valuable medicinal properties of compounds.

12 cl, 2 dwg, 16 ex