FIELD: organic chemistry, chemical technology.
SUBSTANCE: invention relates to a method for synthesis of 8-nitro-1,3,6-triazahomoadamantane. Method involves using nitromethane and derivative of tetraazaadamantane that react in the presence of acetic acid as a catalyst in n-butyl or isopropyl alcohol at weak boiling and wherein 1,3,6,8-tetraazatricyclo[4.3.1.13,8]undecane is used as a derivative of tetraazaadamantane. Reaction is carried out at weak boiling for 20-30 min and synthesized product is extracted with hot heptane and re-crystallized from isopropyl alcohol or acetone. Invention provides enhancing yield and simplifying process in synthesis of the end product.
EFFECT: improved method of synthesis.
2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PRODUCING 8-NITRO-1,3,6-TRIAZAHOMOADAMANTANE | 0 |
|
SU1414848A1 |
| METHOD OF PRODUCING 1,9-DIPHENYL-3,7-DIAZATRICYCLO[5,3,1,1]DODECAN-10-ONE | 2015 |
|
RU2593144C1 |
| METHOD FOR OBTAINING 9-PHENYL-3,6-DIAZATRICYCLO[4.3.1.1]UNDECAN | 2007 |
|
RU2333911C1 |
| METHOD OF PREPARING PYRIDO-(3,2,-E) ASIMM-TRIAZINE DERIVATIVES OR SALTS THEREOF | 0 |
|
SU576941A3 |
| 1,5-BIS[(TERT-BUTYLAMINO)METHYL]-N,N'-DI-TERT-BUTYLBISPIDIN-9-ONE AND METHOD FOR PRODUCTION THEREOF | 2011 |
|
RU2472793C1 |
| METHOD OF PREPARING 4N-BENZO/4,5/-CYCLOHEPTA-/1,2-B/ THIOPHENE DERIVATIVES OR SALTS THEREOF | 0 |
|
SU596169A3 |
| 0 |
|
SU391777A1 | |
| METHYL ESTER OF N-TERT-BUTYROXYCARBONYL-S-PYROLIDONEMETHYLCYSTEINYL-S-PYRROLIDONEMETHYLCYSTEINE AS STARTING PRODUCT FOR SYNTHESIS OF CYSTEINE-CONTAINING PEPTIDES | 0 |
|
SU870396A1 |
| METHOD FOR SYNTHESIS OF NITROMETHANE DERIVATIVES OR THEIRS ALKALINE | 0 |
|
SU1773262A3 |
| NITROMETHANE DERIVATIVES AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF | 1991 |
|
RU2066680C1 |
