METHOD FOR PREDICTING THE RISK OF HEMORRHAGE RELAPSE IN PATIENTS WITH ULCEROUS GASTRIC AND DUODENAL DISEASE Russian patent published in 2008 - IPC A61B10/00 A61B1/273 G01N33/48 

FIELD: medicine, surgery, gastroenterology.

SUBSTANCE: the present innovation deals with predicting the risk of hemorrhage relapse out of acute gastroduodenal ulcers. It is necessary to carry out clinical, laboratory and endoscopic inspection of a patient at detecting and evaluating the following risk factors in points: sex; age; time from the onset of hemorrhage till entering a hospital; the signs of hemorrhagic shock at pre-hospital stage; Algover's index; the content of hemoglobin (g/l); the presence or absence of hypertonic disease; hepatic and pancreatic diseases; localization of ulcerous defect; diameter of ulcerous defect; depth of ulcerous defect (cm); degree of hemorrhage by Forrest. Moreover, additionally as risk factors it is necessary to evaluate the parameters of hemostasis system: the quantity of thrombocytes (*10⁹/l); aggregational activity of thrombocytes (%); radius of aggregates (mcm); prothrombin time PTT (sec); thrombin time TT (sec); activated partial thromboplastin time APTT (sec); level of fibrinogen (g/l); kaolin time of plasma (sec); level of antithrombin III (AT III) (%); level of protein C; XII-a-dependent euglobulin lysis (min); streptokinase-induced lysis (sec); Index of plasminogen reserve (%); level of soluble fibrin-monomer complexes (SFMC) (*10^-2 g/l). Then one should detect the sum of points and then, based upon this sum one should predict either the presence or the absence of the risk of hemorrhage relapse.

EFFECT: higher accuracy of prediction.

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