FIELD: veterinary pharmacology, pharmaceutical technology.
SUBSTANCE: invention proposes a veterinary medicinal agent showing attractive taste. This agent comprises substrate as a granule or tablet that is attractive for animals wherein finely divided particles possessing a physiologically compatible solid carrier with neutral taste are incorporated into substrate. Indicated finely divided particles of carrier have average diameter 0.09-0.8 mm, and a cover prepared from a veterinary active substance is applied on particles wherein layer of an active substance is coated by a protective layer of a physiologically compatible polymeric matrix. Method for preparing a veterinary medicinal agent involves the following steps: (1) cover comprising active substance or veterinary active substance is applied on particles with average diameter 0.09-0.8 mm consisting of physiologically compatible solid carrier of neutral taste to provide the complete covering particles by the active substance; (2) masking protective layer representing physiologically compatible polymeric matrix is applied on this cover comprising active substance, and this protective layer prevents direct contact of active substance with tasting and olfactory cells and saliva of animal; (3) indicated particles having a double cover are mixed thoroughly with substrate that is attractive for animal, and (4) mixture comprising substrate and particles with double cover are pressed to obtain tablets or granules designated for administration. Also, invention describes using indicated finely divided carrier particles with a double cover in preparing a veterinary drug. Invention provides easy administration of veterinary active substances with unfavorable taste in animals.
EFFECT: improved preparing method, improved and valuable properties of compositions.
20 cl, 2 tbl, 5 ex
