FIELD: medicine, neurology.
SUBSTANCE: invention proposes using the known anticonvulsant drug acediprolum (other names of substance - depakin, convulex, sodium valproate) as an agent showing the prophylactic hypoxic and mnemasthenia in acute period of cranial trauma. High protective anticonvulsant index is found firstly in sodium valproate in post-traumatic period in large convulsion attacks in case of its prescription since 2 days after trauma. The course using the preparation both recovers the learning rate of traumatized animals up to the normal levels and stimulates acquiring behavioral adaptive responses being among them reproduction of adaptive responses (method for evaluation of mnemasthenic functions).
EFFECT: valuable medicinal properties of agent.
4 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| MEDICINAL AGENT OFFERING ANTI-ISCHEMIC, ANTIHYPOXIC AND ANTICONVULSANT EFFECT IN CRANIAL TRAUMA | 2005 |
|
RU2309745C2 |
| MEDICATION PRODUCING ANTI-ISCHEMIC, ANTIHYPOXIC AND ANTIAMNESTIC ACTION IN ACUTE PERIODE OF CRANIOCEREBRAL TRAUMA | 2009 |
|
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| MEDICATION, PROVIDING NEURO-PROTECTIVE ACTION IN ACUTE PERIOD OF CRANIOCEREBRAL INJURY | 2009 |
|
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| ANTICONVULSANT AND ANTIHYPOXIC AGENT | 2008 |
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| METHOD OF TREATING CRANIOCEREBRAL INJURY AND AGENT FOR IMPLEMENTATION THEREOF | 2023 |
|
RU2826364C1 |
| APPLICATION OF BETA-HYDROXYBUTYRATE OR ITS PHARMACEUTICALLY ACCEPTABLE SALTS FOR PREPARATION OF MEDICATION WHICH POSSESSES CYTOPROTECTIVE ACTIVITY, INCLUDING NEUROPROTECTIVE, CARDIOPROTECTIVE, ANTI-ISCHEMIC, ANTI-HYPOXIC, ANTI-STRESS, ACTOPROTECTIVE AND ADAPTOGENIC ACTIVITY, MEDICATION AND METHOD OF PREVENTION, RELIEF AND TREATMENT BY MEANS OF SAID MEDICATION | 2009 |
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| METHOD FOR TREATMENT OF CEREBROVASCULAR BRAIN DISORDERS (OPTIONS) | 2017 |
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| REMEDY FOR PREVENTING EDEMA | 1988 |
|
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| NEURORABILITATION AGENT BASED ON SODIUM 6-OXO-1-PHENYL-2-(PHENYLAMINO)-1,6-DIHYDROPYRIMIDINE-4-OLATE | 2018 |
|
RU2675694C1 |
| STRESS-PROTECTIVE AGENT SHOWING ANTIAMNESTIC, ANTIHYPOXIC, ANXIOLYTIC AND ANTI-SHOCK-PRODUCING ACTIONS | 1992 |
|
RU2064793C1 |
