FIELD: medicine.
SUBSTANCE: claimed is application of known anticonvulsant lamotrigine (other names of substance - lamictal, lamolep) as medication, which prevents ischemic and hypoxic disorders in acute period of craniocerebral injury. Demonstrated is prevention of secondary disorders of brain functions as a result of ischemia, hypoxia with hypercapnia, hemic hypoxia with simultaneous facilitation of recovering neuro-physical status.
EFFECT: lamotrigine increases brain stability to major factors of its secondary injury by 24,9-42,6% and improves life duration of mice in post traumatic period by 109,6%.
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| Title | Year | Author | Number |
|---|---|---|---|
| MEDICINAL AGENT SHOWING MULTIFACTOR NEUROPROTECTIVE AND NOOTROPIC EFFECT IN CRANIAL TRAUMA | 2005 |
|
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