FIELD: medicine, pharmacy.
SUBSTANCE: invention proposes a pharmaceutical composition for oral administration that contains iota-carragheenan, one or more neutral gelatinizing polymer and the main pharmaceutically active component. The neutral gelatinizing polymer represents polyethylene oxide, polyethylene glycol, hydroxypropylmethylcellulose or mixture of hydroxypropylmethylcellulose and polyethylene oxide. The main pharmaceutically active component represents preferably metoprolol. The composition inhibits release of the main pharmaceutically active component at acid pH value and creates pH-independent pattern of release.
EFFECT: improved and valuable pharmaceutical properties of composition.
10 cl, 11 dwg, 14 ex
| Title |
Year |
Author |
Number |
| PHARMACEUTICAL PREPARATION WITH MODIFIED ELUTION |
2003 |
- Magnusson Anders
- Tune Mikaehl'
|
RU2352323C2 |
| TIME-RELEASE PHARMACEUTICAL COMPOSITION AND USE THEREOF |
2003 |
- Magnusson Anders
- Tune Mikaehl'
|
RU2474416C2 |
| NOVEL DERIVATIVES OF MANDELIC ACID AND THEIR USING AS THROMBIN INHIBITORS |
2001 |
- Ingkhardt Tord
- Jokhansson Anders
- Svensson Arne
|
RU2300521C2 |
| PHARMACEUTICAL PREPARATION WITH IMMEDIATE RELEASE |
2003 |
- Abrakhmsen Alami Susanna
- Ingkhardt Tord
- Magnusson Anders
- Sigfridsson Karl-Gustaf
- Tune Mikaehl'
|
RU2351314C2 |
| ALMOND ACID DERIVATIVES AND THEIR USE AS THROMBIN INHIBITOR |
2002 |
- Ingkhardt Tor
- Jokhansson Anders
- Svensson Arne
|
RU2341516C2 |
| NEW CRYSTALLINE FORMS |
2007 |
- Oslund Bengt Leonard
- Bengtsson Stefan
- Bergman Gudrun Anita
- Khol'Najkher Ursula Renata Marija
- Imen Bo Ingvar
|
RU2446156C2 |
| THROMBIN INHIBITORS, PHARMACEUTICAL COMPOSITION BASED ON THEREOF, METHOD OF TREATMENT, METHOD OF THEIR SYNTHESIS (VERSIONS) AND PROTECTED DERIVATIVE |
1996 |
- Gustafsson David
- Njustrem Jan-Ehrik
|
RU2176645C2 |
| PEPTIDE DERIVATIVES, THEIR STEREOISOMERS OR PHYSIOLOGICALLY ACCEPTABLE SALTS SHOWING ANTITHROMBOSIS, ANTICOAGULATING OR ANTI-INFLAMMATORY ACTIVITY, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION, METHOD OF SUPPRESSION OF THROMBIN ACTIVITY, METHOD OF INHIBITION OF KININOGENASES ACTIVITY, USE OF COMPOUNDS AS PARENT SUBSTANCES FOR SYNTHESIS OF THROMBIN INHIBITOR |
1994 |
- Karl Tomas Antonsson
- Rut Ehl'Vju Bjulund
- Nil'S David Gustafsson
- Nil'S Olov Ingemar Nil'Sson
|
RU2142469C1 |
| THROMBIN INHIBITOR-CONTAINING AQUEOUS SOLUTION FOR NONPARENTERAL ADMINISTRATION SHOWING STABILITY AT STORAGE |
1995 |
- Ulla St'Ernfel'T
- Mats Sundgren
|
RU2164803C2 |
| PRODRUGS OF THROMBIN INHIBITORS |
1996 |
- Antonsson Tomas
- Gustafsson David
- Khoffmann Kurt-Jurgen
- Njustrem Jan-Ehrik
- Serensen Khenrik
- Sellen Mikaehl'
|
RU2176644C2 |
