FIELD: medicine; pharmaceutical.
SUBSTANCE: invention refers to pharmaceutical formulation and therapeutic method including introduction to related patient of composition 2-alkyliden derivative of 19-nor-vitamin D and bisphosphonate. In particular, this invention refers to pharmaceutical formulation and therapeutic methods including introduction to related patient of 2-methylene-19-nor-20(S)-1α,25- dihydroxyvitamin D3 and bisphosphonate selected from tyludronate, alendronate, zoledronate, ibanedronate, risedronate, ethydronate, clodronate or pamydronate. Stated invention allows increasing of therapeutic efficiency of such diseases as senile osteoporosis, postclimacteric osteoporosis, bone fracture, bone graft, osteopeny and male osteoporosis.
EFFECT: increased therapeutic efficiency.
18 cl, 2 ex, 2 tbl
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| APPLICATION OF VITAMIN D DERIVATIVES IN TREATING OSTEOPOROSIS AND RELATED OSSEOUS DISEASES, AND, ALSO, NEW VITAMIN D3 DERIVATIVES | 2001 |
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| CYSTEIC CATHEPSIN PROTEASE INHIBITOR | 2005 |
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