NOVEL INTERMEDIATE COMPOUNDS FOR SYNTHESIS OF VITAMIN D DERIVATIVES Russian patent published in 2008 - IPC C07F7/18 C07D303/12 

Abstract RU 2317992 C2

FIELD: organic chemistry, chemical technology, vitamins.

SUBSTANCE: invention relates to novel intermediate compounds used for synthesis of derivatives of vitamin D and represented by the formula (I): wherein Y1 represents hydrogen atom or tert.-butyldimethylsilyl group; Y2 represents tert.-butyldimethylsilyl group; Y3 represents hydrogen atom or tetrahydro-2-pyranyl group wherein Y3O-group is in R-configuration; R1 and R2 are bound and form methylene group. Except for, invention relates to novel compounds represented by the formula (II): wherein Y2 represents tert.-butyldimethylsilyl group; Y3 represents hydrogen atom or tetrahydro-2-pyranyl group and Y3O-group is in R-configuration. These compounds are used as intermediate substances for synthesis of compounds of the formula (I).

EFFECT: valuable properties of intermediate compounds.

8 cl, 1 dwg, 8 ex

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Authors

Imakhori Khidekazu

Kojama Khiroja

Josikhara Dajsuke

Savasita Josinori

Kurita Sota

Itikhara Josikhiro

Takagi Josikhiro

Khirose Katsutosi

Dates

2008-02-27Published

2004-02-18Filed