COMPLEX COMPOUND 1,3-BIS(2-HYDROXYETHYL)-5-HYDROXY-6-METHYLURACIL WITH FUMARIC ACID THAT EXHIBITS ANTI-HYPNOTIC ACTIVITY AND METHOD OF OBTAINING IT Russian patent published in 2008 - IPC C07D239/60 A61K31/513 A61P9/10 

Abstract RU 2330025 C2

FIELD: chemistry.

SUBSTANCE: invention relates to the new complex compound of 1,3-bis(2-hydroxyethyl)-5-hydroxy-6-methyluracil with fumaric acid of the formula which can be used in medicine as the substance capable of raising the survival rate in conditions under the influence of extreme environmental factors, particularly hypoxia. The new complex compound 1,3-bis(2-hydroxyethyl)-5-hydroxy-6-methyluracil with fumaric acid is obtained with 94% output by mixing equimolar quantities of 1,3-bis(2-hydroxyethyl)-5-hydroxy-6-methyluracil with fumaric acid in organic solvent with the subsequent heating of the reaction mixture for 2-3 hours, preferably at a temperature of 60-70°, removal of the solvent from the reaction mixture and the isolation of the product.

EFFECT: it makes it possible to increase the survival rate in harsh environmental conditions.

3 cl, 3 tbl, 5 ex

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RU 2 330 025 C2

Authors

Krivonogov Viktor Petrovich

Myshkin Vladimir Aleksandrovich

Ibatullina Rifa Barievna

Abdrakhmanov Il'Dus Barievich

Mustafin Akhat Gaziz'Janovich

Bakirov Akhat Barievich

Gimadieva Al'Fija Raisovna

Chernyshenko Julija Nikolaevna

Savlukov Aleksandr Ivanovich

Srubilin Dmitrij Vital'Evich

Dates

2008-07-27Published

2006-05-10Filed