ANALOGUES OF 1-DEAMINO-8-D-ARGENYLE VASOPRESSIN Russian patent published in 2008 - IPC C07K7/16 A61K38/11 

Abstract RU 2330044 C2

FIELD: chemistry.

SUBSTANCE: new analogues 1-deamino-8-D-arginylvassopressin, which have the following general formula: Mpa-Tyr-Phe-X-Y-Cys-Pro-D-Arg-Gly-NH2, where Mpa is the radical of 3-mercaptoproprionic acid with the formula: SH-CH2-CH2-COOH; X is the amino group which includes alanine, asparagines, glutamine, isoleucine, leucine and valine, Y is an amino-acid from the group, which includes glutamine, isoleucine, leucine and valine. Analogues 1-deamino-8-D-argenyle vasopressin, which has the following formula: where Mpa is the radical of 3-mercaptoproprionic acid with the formula: SH-CH2-CH2-COOH; X is the amino group which includes alanine, asparagines, glutamine, isoleucine, leucine and valine, Y is an amino-acid from the group, which includes glutamine, isoleucine, leucine and valine.

EFFECT: products possess increased effectiveness.

14 cl, 6 dwg, 3 tbl, 8 ex

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RU 2 330 044 C2

Authors

Gomez Daniehl E.

Alonso Daniehl F.

Ripoll Giselli V.

Giron Sant'Jago

Dates

2008-07-27Published

2003-12-29Filed