FIELD: medicine.
SUBSTANCE: invention suggests pharmaceutical compositions intended for sublingual intake, as active ingredient of which agonist of central receptor of benzodiazepines is used, selected from the following list: diazepam, lorazepam, bromazepam, triazolam, alprazolam, flunitrazepam, nitrazepam, midazolam-maleate, in mixture with pharmaceutical excipient, which constitutes at least 70% of total weight of ready composition, and which contains lactose in amount from 40 to 45 wt %, corbite in amount from 15 to 27 wt % and cellulose in amount from 12 to 16 wt %. Excipient components lactose: cellulose: corbite are in ratio, approximately, 3:1,4-2,7:1.
EFFECT: ensuring fast action of benzodiazepines, similar to action of analogous preparations for injections and higher action than after peroral intake.
7 cl, 4 tbl, 8 ex
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Authors
Dates
2008-10-10—Published
2004-05-26—Filed