PHARMACEUTICAL COMPOSITION BASED ON BENZODIAZEPINE AGONIST Russian patent published in 2008 - IPC A61K31/55 A61K31/5513 A61K47/38 A61K47/26 A61K9/20 A61P25/20 A61P25/00 A61P23/00 A61P21/02 

Abstract RU 2335288 C2

FIELD: medicine.

SUBSTANCE: invention suggests pharmaceutical compositions intended for sublingual intake, as active ingredient of which agonist of central receptor of benzodiazepines is used, selected from the following list: diazepam, lorazepam, bromazepam, triazolam, alprazolam, flunitrazepam, nitrazepam, midazolam-maleate, in mixture with pharmaceutical excipient, which constitutes at least 70% of total weight of ready composition, and which contains lactose in amount from 40 to 45 wt %, corbite in amount from 15 to 27 wt % and cellulose in amount from 12 to 16 wt %. Excipient components lactose: cellulose: corbite are in ratio, approximately, 3:1,4-2,7:1.

EFFECT: ensuring fast action of benzodiazepines, similar to action of analogous preparations for injections and higher action than after peroral intake.

7 cl, 4 tbl, 8 ex

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RU 2 335 288 C2

Authors

Vandoni Gvido

Oliani Karlo

Soelkho Adriano

Zaniboni Kheni

Dates

2008-10-10Published

2004-05-26Filed