ORALLY DISINTEGRATING TABLET TEMAZEPAM COMPOSITIONS Russian patent published in 2014 - IPC A61K9/20 A61K31/5513 A61K47/30 A61K45/08 A61P25/00 

Abstract RU 2524638 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to the chemical-pharmaceutical industry and represents an orally disintegrating tablet composition, which includes particles of a therapeutic preparation, containing: a therapeutically effective quantity of, at least, one therapeutic preparation; 0.5-3% ODT binding polymer; sugar alcohol and/or saccharide; and a disintegrant, with particles of the therapeutic preparation being prepared by granulation of, at least, one therapeutic preparation, sugar alcohol and/or saccharide and the disintegrant in the presence of the ODT binding polymer, where the composition mainly disintegrates within approximately 30 seconds after contact with saliva in the oral cavity or in testing by a disintegration test <USP 701>.

EFFECT: drug form can be applied in elderly patients and patients with swallowing disorders.

28 cl, 8 dwg, 13 tbl, 5 ex

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RU 2 524 638 C2

Authors

Venkatesh Gopi

Klivendzher Dzhejms

Lai Dzin-Vang

Purokhit Vivek

Dates

2014-07-27Published

2008-12-19Filed