FIELD: medicine; chemical and pharmaceutical industry.
SUBSTANCE: invention in the field of pharmaceutical forms, in particular relates to a regulated delivery tablet held in the stomach containing: a) a centre regulating medicine release which contains medicine, well expanding polymer, generating gas-agent, and b) a composition of fast releasing coating with the same medicine as in the centre and pharmaceutically accepted accipients, where the coating envelops the centre which ensures two-phase medicine release in the gastro-intestinal fluid. Besides, the invention is associated with once a day therapy, which includes centre with baclofen released in a regulated manner and coating of fast release composition made of baclofen or its pharmaceutically acceptable salt and pharmaceutically accepted filling material and means for holding the tablet in the stomach for longer periods.
EFFECT: holding tablets in the stomach for longer periods; two-phase medicine delivery in a regulated manner.
14 cl, 1 dwg, 6 tbl, 4 ex
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