METHOD OF DIAGNOSTICS OF EPILEPTIC SYNDROME OF ALCOHOLIC GENESIS Russian patent published in 2008 - IPC A61B5/476 A61B8/13 G01N33/48 

Abstract RU 2337615 C1

FIELD: medicine; neurology.

SUBSTANCE: detect presence of signs and estimate their score. Anamnesis data: positive screening tests for presence of a chronic drunkenness - 5.6 points; absence of epiphenomenons - 9.0 points; absence of the heredity burdened on an epilepsy - 11.6 points; absence of the traumas, tumours of a brain, strokes - 11.0 points. Data of clinical survey: a polyneuropathy of the muscular cramps - 4.7 points; absence of focal symptoms, pyramidal insufficiency and paresises - 10.8 points; tremor, hyperhidrosis - 5.6 points. Then detect presence of only one of the signs with its estimation in points. The data of electroencephalographies: dominating alpha - rhythm with the maximum amplitude to 100 mkv in occipital parts in the absence of pathological rhythms and phenomena on EEG - 1 point; epileptic activity in the form of spikes, categories "peak - acute wave", "acute wave - slow wave" on EEG - 1.3 points; relative epileptic activity in the form of the hypersynchronous pointed alpha rhythm, categories bilaterally synchronous polyphase an alpha of similar waves amplitude above a background in 2 times on EEG 1.3 points; focal activity in a kind slow - wave activity mainly in the aflicted parencephalon on EEG - 1.1 points; dysfunction of medio-stem structures in the form of individual categories of bilaterally synchronous polyphase alpha-type waves with amplitude at level of background, smoothness of zone differences on EEG - 1.9 points; low bioelectric activity, easy diffusive changes of the brain, "flat" type of curves on EEG - 6.1 points. Brain tomography data: cystic-glial brain changes - 1.6 points; absence of expansion of subarachnoid spaces, shifts of median structures, sites of pathological density, deformation of ventricles and cisterns of the basis of brain - 2.8 points; mixed hypotrophic hydrocephaly of brain - 8.2 points. Data of laboratory methods of the analysis: indicators GPT and GOT up to 40 units, GGTP up to 50 units (Si) - 6.8 points; the increased indicators of one or all enzymes: GPT and GOT above 40 units, GGTP above 50 units (Si) - 5.8 points. The received points are summarised and at a score from 8.4 to 43.7, the degree of probability of an epileptic syndrome of an alcoholic genesis is diagnosed as low, from 43.8 to 76.5 - as average, from 76.6 to 79.4 as high.

EFFECT: method expands an arsenal of agents of differential diagnostics of an epileptic syndrome of an alcoholic genesis.

2 tbl, 3 ex

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RU 2 337 615 C1

Authors

Sidorov Pavel Ivanovich

Solov'Ev Andrej Gorgon'Evich

Elistratova Tat'Jana Vladimirovna

Dates

2008-11-10Published

2007-01-18Filed