MEANS OF IDENTIFICATION OF TUMOURS, ACQUISITIVE TO TREATMENT BY ANTIBODIES AGAINST ErbB2 Russian patent published in 2008 - IPC C07K14/485 G01N33/53 

Abstract RU 2338751 C2

FIELD: biology.

SUBSTANCE: method of identification of tumours, acquisitive to treatment by a monoclone 2C4 either its functional fragment or a monoclone possessing biological characteristics of a monoclone 2C4 or its functional fragment is described. Reveal presence of albuminous complex HER2/HER3 and/or HER2/HER1 in the sample of a tumour. Then define a tumour sensibility to treatment by the specified antibody or its fragment after detection of presence of a complex.

EFFECT: present invention allows to identify simply a tumour, acquisitive to treatment by an antibody 2C4.

22 cl, 8 dwg, 1 tbl, 7 ex

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RU 2 338 751 C2

Authors

Koll' Khans

Bossenmajer Birgit

Mjuller Khans-Joakhim

Slivkovski Mark K.

Kelsi Stefen Majkl

Dates

2008-11-20Published

2003-07-11Filed