FIELD: medicine, oncology, immunology.
SUBSTANCE: invention relates to humanized antibodies with ErbB2. Invention involves the development of new humanized antibodies raised to tyrosinase receptors of family ErbB2, and to a composition comprising these antibodies. The advantage of invention involves expanding region in using indicated antibodies in cancer treatment wherein receptor of epidermal growth factor, EGFR, is a target of these antibodies.
EFFECT: valuable properties of antibody.
14 cl, 3 tbl, 13 dwg
| Title |
Year |
Author |
Number |
| MEANS OF IDENTIFICATION OF TUMOURS, ACQUISITIVE TO TREATMENT BY ANTIBODIES AGAINST ErbB2 |
2003 |
- Koll' Khans
- Bossenmajer Birgit
- Mjuller Khans-Joakhim
- Slivkovski Mark K.
- Kelsi Stefen Majkl
|
RU2338751C2 |
| THERAPY OF MALIGNANT TUMOR, RESISTANT TO PLATINUM-BASED MEDICATIONS |
2005 |
|
RU2403065C2 |
| COMPOSITION OF HER2 ANTIBODIES |
2005 |
- Kao Jun-Sian
- Vanderlan Martin
|
RU2361880C2 |
| COMPOSITION CONTAINING ANTIBODY BINDING TO DOMAIN II OF HER2, AND ITS ACIDIC VERSIONS |
2009 |
- Kharris, Rid, Dzh.
- Motchnik, Pol, A.
|
RU2543664C2 |
| PHARMACEUTICAL COMPOSITIONS AIMED AT Erb-B1 RECEPTORS |
2003 |
- Krejsh Khans-Georg
- Shmidt Jurgen
|
RU2354402C2 |
| INTRODUCTION OF FIXED DOSES OF HER-ANTIBODIES |
2005 |
- Ehllison Dehvid E.
- Brjuno Rene
- Lu Tszjan'-Fyn
- Ng Chee M.
|
RU2438705C2 |
| COMPOSITIONS OF ANTIBODIES |
2005 |
- Ehnd'Ja Dzhejms D.
- Gvi Shian K.
- Lju Tszjun'
- Shehn' E
|
RU2426554C2 |
| COMBINED THERAPY USING INHIBITORS OF TYROSINE KINASE RECEPTORS AND INHIBITORS OF ANGIOGENESIS |
2001 |
- Gudman Sajmon
- Krejsh Khans-Georg
|
RU2292904C2 |
| SELECTION OF MEDICATIONS FOR LUNG CANCER THERAPY BY MEANS OF ANTIBODY-BASED MATRICES |
2008 |
- Singkh Sharat
- Kharvi Zhanna
|
RU2519647C2 |
| SINGLE-DOMAIN MINI-ANTIBODY aHER2/aSKBR3-1, SPECIFICALLY BINDING EPIDERMAL GROWTH FACTOR RECEPTOR HER2/ERBB2/neu AND CAPABLE TO PENETRATE THROUGH THIS INTERACTION INTO TARGET CELLS (INTERNALISED), METHOD OF PRODUCTION OF THIS ANTIBODY AND METHOD OF DETECTION OF PROTEIN HER2/ERBB2/neu AND CELLS EXPRESSING THIS PROTEIN IN INCREASED AMOUNT, USING MINI-ANTIBODY aHER2/aSKBR3-1 |
2012 |
- Tillib Sergej Vladimirovich
- Ivanova Tat'Jana Il'Inichna
- Vasil'Ev Lev Anatol'Evich
- Deev Sergej Mikhajlovich
- Zdobnova Tat'Jana Aleksandrovna
- Zagajnova Elena Vadimovna
|
RU2522929C2 |
