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2 339 373

(13)

(51)

IPC

A61K31/401(2006-01-01)

A61P25/08(2006-01-01)

A61K31/515(2006-01-01)

(21) (22)

Application

2007112569/14, 2007-04-04

(24)

Start date

2007-04-04

(22)

Actual filing date

2007-04-04

(45)

Published

2008-11-27

(72)

Inventor

Shirjaev Oleg Jur'EvichPolozova Tat'Jana MikhajlovnaShapovalov Denis LeonidovichRogozina Marina Anatol'Evna

(73)

Holder

Gosudarstvennoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Gosudarstvennaja Meditsinskaja Akademija Im. N.N. Burdenko Federal'Nogo Agentstva Po Zdravookhraneniju I Sotsial'Nomu Razvitiju"

METHOD FOR EFFICIENCY INCREASE IN TREATMENT FOR EPILEPSY Russian patent published in 2008 - IPC A61K31/401 A61P25/08 A61K31/515

Abstract RU 2339373 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, particularly to psychiatry; it can be applied in adult patient with disease duration 10 years and over, and symptomatic arterial hypertension. At arterial pressure (AP) maximum value of 160/100 mm Hg, and absence of hyperkaliemia and/or chronic renal impairment symptoms, standard anti-epileptic complex therapy is administered; if satisfactory response not obtained, additionally starting dose 2.5 mg of lisinopryl is injected, anti-epileptic drugs dosage being left unchanged. If the response is satisfactory, showing clinical remission or fits frequency reducing two times and more, anti-epileptic drugs dosage is lowered or anti-epileptic drugs monotherapy is administered.

EFFECT: eliminates chronic hypoxia of neural tissue, hypernatremia, hypokaliemia, neural tissue hyperhydration; allows anti-epileptic drugs dosage lowering.

3 cl, 4 tbl

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RU 2 339 373 C1

Authors

Shirjaev Oleg Jur'Evich

Polozova Tat'Jana Mikhajlovna

Shapovalov Denis Leonidovich

Rogozina Marina Anatol'Evna

Dates

2008-11-27—Published

2007-04-04—Filed