METHOD FOR OBTAINING FRONDOSIDE A AND METHOD OF IMMUNE SYSTEM STIMULATION FOR MAMMALS Russian patent published in 2008 - IPC C07J71/00 A61K35/56 A61P37/04 

Abstract RU 2339644 C2

FIELD: chemistry, immunology.

SUBSTANCE: extraction of dried cook water of sea cucumber Cucumaria frondosa or dried powder tissues of Cucumaria frondosa by chloroform and methanol mix is performed during boiling with reflux condenser to obtain organic extract; extract is evaporated, evaporated extract is re-dissolved in water, obtained colloid solution is decanted, ethylacetate is added to solution, water phase is decanted and undergoes chromatography in teflon or silica gel columns. Immune system activity of mammals, including lizosomic activity, phagocitosis and active oxygen form generation in macrophags of mammals, infected with bacterial cells, viruses and protozoa, is stimulated by oral, intraperitoneal or intramuscular or combined introduction of frondosite A dosage of 1 to 15 mcg/kg, preferably 10 mcg/kg.

EFFECT: implementation of claimed objective.

11 cl, 18 ex

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RU 2 339 644 C2

Authors

Avilov Sergej Anatol'Evich

Kalinin Vladimir Ivanovich

Sil'Chenko Aleksandra Sergeevna

Aminin Dmitrij L'Vovich

Agafonova Irina Grigor'Evna

Stonik Valentin Aronovich

Kollin Piter D.

Vudvord Karl

Dates

2008-11-27Published

2005-06-03Filed