CARRIER OF ANTIGENS Russian patent published in 2008 - IPC A61K39/39 C07H3/06 C07H15/24 

FIELD: biotechnology, immunology.

SUBSTANCE: invention proposes a carrier of antigens as a lipid complex consisting of glycoside, cholesterol and lipid. As glycoside a carrier comprises holotoxin A₁, and as lipid - monogalactosyldiacyl glycerides (MGDG) of sea macrophytes taken in the weight ratio 3 (holotoxin A₁) : 2 (cholesterol) : (2-6) (MGDG). Prepared glycoside-cholesterol-lipid carrier shows stretched threadlike-tubular structure. Use of the prepared carrier of antigens allows enhancing the immunogenic activity of vaccine preparations, and to decrease or remove completely hemolytic toxicity of holotoxin A₁, and to eliminate inflammatory, painful, toxic and hemolytic effects of vaccines.

EFFECT: improved and valuable medicinal properties of carrier and vaccines.

4 dwg, 11 ex