HYDROCHLORIDE 8-AMINO-7-(2-HYDROXYPROPYL-1)-1,3-DIMETHYLXANTHINE DERIVATIVES DISPLAYING HAEMORHEOLOGICAL ACTIVITY Russian patent published in 2009 - IPC C07D473/08 A61K31/522 A61P7/02 

Abstract RU 2344137 C1

FIELD: chemistry.

SUBSTANCE: invention refers to new derivatives of hydrochloride 8-amino-7-(2-hydroxypropyl-1)-1,3-dimethylxanthine of general formula: where . Compounds under this invention display haemorheological activity surpassing that of common pentoxifylline compound. Compounds represent hydrochloride 1,3-dimethy-7-(2-hydroxy-3- piperidinopropyl-1)-8-phenylaminoxanthine or hydrochloride 1,3- dimethy-7-[2-hydroxy-3-(2- chlorophenoxy)-propyl-1]-8- piperazinoxanthine.

EFFECT: production of compounds displaying haemorheological activity.

4 cl, 2 tbl, 4 ex

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RU 2 344 137 C1

Authors

Nazipov Nail' Mansurovich

Spasov Aleksandr Alekseevich

Khaliullin Ferkat Adel'Zjanovich

Naumenko Ljudmila Vladimirovna

Davlet'Jarova Al'Pija Vasil'Evna

Dates

2009-01-20Published

2007-07-18Filed