FIELD: medicine.
SUBSTANCE: invention concerns medicine and claims plaster for local application, containing capsaicin or its analogue, method of its manufacturing, and application. Invention concerns plaster for local application, including substrate layer impermeable for therapeutic compound, self-gluing matrix based on polysiloxanes and containing capsaicin or therapeutic compound similar to capsaicin, and protection film removed before application; where matrix includes microreservoirs for fluid based on amphiphilic solvent in which therapeutic compound is placed in completely dissolved form, and concentration of therapeutic compound in microreservoir drops is lower than saturation concentration. Invention claims method of plaster production and application in neuropathological pain mitigation.
EFFECT: system stability required for high grade of active component deliberation.
15 cl, 4 tbl, 3 dwg, 5 ex
