FIELD: medicine.
SUBSTANCE: there is described a transdermal therapeutic system (5) containing a substrate (1), an adhesion layer (4), a polymer layer (2) and a detached protective coating (3). The adhesion layer (4) is organopolysiloxane and is fixed on the substrate (1) by siliconisation.
EFFECT: improved bonding strength of the substrate in the transdermal therapeutic system and the polymer layer containing biologically active substances and at least one silicon bonding agent.
7 cl, 1 dwg
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