FIELD: biology; biotechnology.
SUBSTANCE: invention concerns biotechnology. It claims linking molecule represented by monoclonal antibody or its fragment capable of binding human NogoA polypeptide, human NogoA 623-640. Polynucleotide encoding the claimed molecule is presented. Expression vector including indicated polynucleotide is described. Host cell including indicated polynucleotide or vector is described. Pharmaceutical composition for treatment of diseases related to nerve reconstruction and containing indicated molecule is described.
EFFECT: obtainment of antibodies capable of binding NogoA 623-640.
9 cl, 1 dwg, 3 tbl, 7 ex
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