METHOD OF CANCER OF RECTUM TREATMENT Russian patent published in 2009 - IPC A61B17/00 A61N5/10 A61K35/14 A61K35/16 A61K31/513 A61P35/00 

Abstract RU 2352264 C2

FIELD: medicine.

SUBSTANCE: invention concerns medicine, namely, oncology, and can be used in complex treatment of cancer of rectum. Essence of the invention consist that in the postoperative period before the beginning of radial therapy of 200 ml autoblood sampling is made, autoleukomass is allocated with the method of centrifugation from blood. Then it is placed 20 ml of the autoleukomass and 1000 mg of the 5-FU in the first vial, in the second vial - the remained formulated elements of blood and plasma, the vials with contents are incubated separately within 40 minutes at 37°C. The autoleukomass with 5-FU from the first vial is administered in intraintestinal manner into nonfunctioning intestine of the double-barrel colostomy, autoblood from the second vial is reinfused intravenously driply, then sessions of radial treatment are spent. Irradiation is made in a regimen of classical fractionating with a single dose of 2 Gy within 5 sessions in a week on primary tumour to the general dose of 40-70 Gy, the intraintestinal chemotherapy on autoleukomass with intravenous autohemotherapy is repeated once a week throughout a course of radial treatment.

EFFECT: method allows to enlarge efficiency of radial therapy, to reduce perifocal inflammation, to move patients in the resectable condition, to reduce frequency of postoperative and radial complications.

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Authors

Sidorenko Jurij Sergeevich

Orlovskaja Lidija Aleksandrovna

Soldatkina Natal'Ja Vasil'Evna

Emel'Janova Larisa Ehrlenovna

Dontsov Vladimir Aleksandrovich

Dzhabarov Farkhad Rasimovich

Dates

2009-04-20Published

2007-03-29Filed