FIELD: medicine.
SUBSTANCE: invention concerns medicine, particularly oncology, and can be applied in complex rectus cancer treatment with removed two-end colostomy. Invention substance involves sampling of 200 ml of patient's autoblood in post-operation period after two-end sigmostoma removal. Then autoplasma is separated from blood by centrifugation method, 50 ml of autoplasma and 1000 mg of 5-fluorouracil is placed in first bottle and remaining blood and plasma elements are placed in the second bottle. Bottles are incubated separately for 40 minutes at 37°C. Then autoplasma with 5-fluorouracil from the first bottle is administered intratestinally to non-functioning intestine of two-end colostoma; autoblood from second bottle is reinfused intravenously by drop infusion, followed by first radiation treatment session. Intratestinal chemotherapy with autoplasma with intravenous autohemotherapy is repeated one time per week during the whole radiation therapy course.
EFFECT: enhanced efficiency of radiation treatment due to direct effect of 5-fluorouracil on tumour and to radio-sensibilising effect; possible transfer of patients to respectable condition and reduced radiation complication rate.
2 ex
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Authors
Dates
2009-03-20—Published
2007-03-29—Filed