ANTIHYPOTENSION MEDICATION Russian patent published in 2009 - IPC C07C335/32 A61K31/27 A61P9/02 

Abstract RU 2353614 C1

FIELD: chemistry.

SUBSTANCE: claimed invention relates to application of compounds of general formula I where R1=H, CH3CO, C2H5CO, CH2=CHCO, CH2=C(CH3)CO, C6H5CO, m-FC6H4CO, m-ClC6H4CO, BrC11H22CO. R2=CH3, C2H5, n-C3H7, i-C3H7, C4H9, C4H8F, C2H4F, C2H4OH, CH2=CH-CH2-, CH2-CH-CH2 X=Cl, Br, I, dialkylphosphate, methane sulfonate, as hypotensive medication. In duration of hypertensive action proposed substances exceed mesatone and other medications, applied in medical practice for hypotensive condition treatment. Also described is pharmacological composition, based on formula I compounds.

EFFECT: obtaining of medication, which in duration of action exceeds mesatone and other medications, applied in medical practice for hypotensive condition treatment.

3 cl, 4 tbl, 6 ex

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RU 2 353 614 C1

Authors

Proskurjakov Sergej Jakovlevich

Verkhovskij Jurij Grigor'Evich

Filimonova Marina Vladimirovna

Shevchenko Ljudmila Ivanovna

Mandrugin Andrej Aleksandrovich

Trofimova Tat'Jana Petrovna

Fedoseev Vladimir Mikhajlovich

Dates

2009-04-27Published

2007-11-06Filed