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2 506 082

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IPC

A61K31/54(2006-01-01)

A61P9/00(2006-01-01)

(21) (22)

Application

2011120567/15, 2011-05-24

(24)

Start date

2011-05-24

(22)

Actual filing date

2011-05-24

(45)

Published

2014-02-10

(72)

Inventor

Mandrugin Andrej AleksandrovichTrofimova Tat'Jana PetrovnaBorisova Galina SergeevnaFilimonova Marina VladimirovnaShevchenko Ljudmila IvanovnaMakarchuk Viktorija MikhajlovnaProskurjakov Sergej Jakovlevich

(73)

Holder

Gosudarstvennoe Uchebno-Nauchnoe Uchrezhdenie Khimicheskij Fakul'Tet Moskovskogo Gosudarstvennogo Universiteta Im. M.V. LomonosovaFederal'Noe Gosudarstvennoe Bjudzhetnoe Uchrezhdenie Meditsinskij Radiologicheskij Nauchnyj Tsentr Minzdravsotsrazvitija Rossii

ANTIHYPOTONIC AGENT Russian patent published in 2014 - IPC A61K31/54 A61P9/00

Abstract RU 2506082 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to antihypotonic agents representing 2-amino-5,6-dihydro-4H-1,3 triazine salts that may be used for creating therapeutic agents for treating hypotension caused by a severe blood loss. What is presented is using seven 2-amino-5,6-dihydro-4H-1,3 triazine salts of general formula I wherein HX=HBr; 2-(AcO)C₆H₄COOH; 2-(OH)C₆H₄COOH; CH₃(CH₂)₁₄COOH; 3,4-(OMe)₂ C₆H₃CH₂COOH; C₆H₅CH₂COOH; HOOCCH₂CH₂COOH, as an antihypotonic agent for treating hypotension caused by a severe blood loss, and a based pharmacological composition for the same applications.

EFFECT: what is shown is the manifested hypotensive property of the known chemical substance in the presence of a severe blood loss.

3 cl, 13 tbl

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RU 2 506 082 C2

Authors

Mandrugin Andrej Aleksandrovich

Trofimova Tat'Jana Petrovna

Borisova Galina Sergeevna

Filimonova Marina Vladimirovna

Shevchenko Ljudmila Ivanovna

Makarchuk Viktorija Mikhajlovna

Proskurjakov Sergej Jakovlevich

Dates

2014-02-10—Published

2011-05-24—Filed