METHOD OF PRODUCING GINKGO BILOBA EXTRACT, EXTRACT PRODUCED THEREBY, AND ITS APPLICATION Russian patent published in 2009 - IPC A61K36/16 A61P25/28 

FIELD: medicine.

SUBSTANCE: invention refers to pharmaceutics. Production of ginkgo biloba extract with low content of 4'-O-methylpyridoxine and/or biflavones involves the stages as follows: (a) production of ginkgo biloba solution in a solvent, (b) application of the solution on an adsorbing resin chosen from styrene copolymer and divinylbenzene or bromated styrene copolymer and divinylbenzene, and elution of the purified extract from adsorbing resin by a solvent, with biflavones kept on the adsorbing resin and/or (c) application of the solution on a strong-acid ion exchanger and elution of the purified extract from the ion exchanger with a solvent with 4'-O-methylpyridoxine kept on the ion exchanger. The solvent at the stages (a), (b) and (c) is independently chosen from aqueous alkanole containing 1-3 carbon atoms, and aqueous ketone containing 3-6 carbon atoms, and (d) concentration and drying of the extract solution to prepare the dry extract with 4'-O-methylpyridoxine not exceeding 20 w.f. and/or biflavone content not exceeding 25% of content in the original extract. Ginkgo extract is applied for making a medical product for treatment of dementia and its symptoms and/or cerebral and peripheral blood circulation disturbances, or a food additive. The medical product or food additive for treatment of dementia and its symptoms and/or cerebral and peripheral blood circulation disturbances is characterised by ginkgo extract content.

EFFECT: invention allows producing extract with low content of 4'-O-methylpyridoxine and/or biflavones.

11 cl, 2 tbl, 6 ex