METHOD OF CRITICAL LOWER EXTREMITY ISCHEMIA TREATMENT Russian patent published in 2009 - IPC A61K31/5575 A61K33/14 A61K35/16 A61P9/10 

Abstract RU 2357735 C1

FIELD: medicine.

SUBSTANCE: invention concerns medicine, particularly vascular surgery, and can be applied in treatment of critical lower extremity ischemia. Method involves sampling of 400-500 ml of blood from vein. Blood is centrifuged for 15 minutes at 2000 rpm rate. Separated erythrocyte mass is dissolved by 200 ml of 0.9% physiological solution and returned to patient intravenously. 20 mcg of vasaprostan medication is added to 200 ml of plasma. Obtained mix is placed in thermostat and incubated for 20 minutes at 37°C, then injected to patient slowly by intravenous drop infusion for 2-3 hours once per day for 10 days.

EFFECT: elevated peripheral arterial pressure, ischemia grade regress, resulting in larger pain-free walking distance.

1 tbl, 2 ex

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RU 2 357 735 C1

Authors

Sukhorukov Aleksandr Mikhajlovich

Tolstikhin Vladimir Jur'Evich

Lavrov Roman Nikolaevich

Pozdnjakov Artem Arkad'Evich

Popenko Andrej Nikolaevich

Rjabkov Igor' Aleksandrovich

Shumakov Pavel Viktorovich

Makarova Anastasija Olegovna

Dates

2009-06-10Published

2008-03-18Filed