PERSISTENT WOUND HEALING APPROACH IN PATIENTS SUFFERING FROM PANCREATIC DIABETES Russian patent published in 2009 - IPC A61K38/58 A61P17/02 A61B17/56 

FIELD: medicine.

SUBSTANCE: persistent wound and trophic ulcer healing in the patients suffering from pancreatic diabetes is ensured by application of medicinal leeches on the wound surface 2-3 times a day followed by application of ointment Piyavit within preparation of the wound surface. The procedure follows until the entire ulcerous bottom is filled with granulation tissue. Then skin flap pre-cured with the ointment Piyavit is transplanted. From the first postoperative days, medicinal leeches are applied on the skin flap in number of 1-3 pieces per a session for course 8-10 days. Then the operative wound is closed with a sterile dressing applied over bandage with ointment Piyavit. The whole therapeutic course involves introduction of capsulated Piyavit in dose 300 mg 2 times a day.

EFFECT: reduced intensity of inflammatory reaction; accelerated start of wound healing with decreased area and reduced recurrence.

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