THERAPY OF BONE METASTASES IN BREAST CANCER Russian patent published in 2009 - IPC A61K31/57 A61K35/24 A61K33/14 A61K38/02 A61P35/00 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to oncology, and can be used in therapy of breast cancer with bone metastasis. Substance of the invention consists in puncture with a needle between III and IV lumbar vertebras in subarachnoid spinal marrow space. Cerebrospinal fluid in amount 2 ml is poured in a sterile bottle and added with Epitalamine 10 mg. The bottle is incubated in a thermostat at temperature 37°C within 20 minutes. Then the prepared mixed liquor and Epitalamine are introduced back into subarachnoid space that is combined with introduction of hydrocortisone 125 mg. The therapeutic course includes 4 lumbal punctures with introduction of preparations once a week.

EFFECT: application of the invention provides regress of bone metastases, reduced toxic collateral reactions of hormonotherapy, immune correction ensured by combined endoliquor introduction of said agents.

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