FIELD: medicine.
SUBSTANCE: invention relates to medicinal agents, particularly to pharmaceutical compositions for local and external application during menopausal disorders, containing sygethin, a base, target additive, with the following ratio of components (wt %): sygethin - 0.001-2.0; target additive - 0.000001-42.6; base - the rest. The base is in form of hydrophilic and/or hyperosmolar substances and the target additive is in form of substances chosen from: vitamins, biogenic elements, antioxidants or their physiologically acceptable mixture.
EFFECT: wide area of application of known sygethin preparation, increased bioavilability of the preparation without violating integrity of the skin; intense therapeutic effect of sygethin.
5 cl, 18 ex
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