BIODEGRADED GLUCOSAMINE MURAMYL PEPTIDES FOR APOPTOSIS MODULATION Russian patent published in 2009 - IPC A61K38/16 

Abstract RU 2363490 C2

FIELD: medicine.

SUBSTANCE: invention concerns biotechnology. The biodegraded apoptosis-modulating glucosamine muramyl peptide, received by hydrolysis of Gram-positive bacteria by specific endopeptidases is described. The way of treatment of disease state characterised by the increased level of lactate dehydrogenase, way of inhibition cytotoxic and pleiotropic action of the tumour necrosis factor alpha (TNF-alpha), way decreasing production of lactate dehydrogenase, including the stage of biodegraded glucosamine muramyl combinations introduction are desribed.

EFFECT: reception of a biodegraded apoptosis-modulating glucosamine muramyl peptide which can be used for control and treatment of the conditions caused by cytotoxicity of the tumour necrosis factor alpha.

17 cl, 2 dwg, 5 ex

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RU 2 363 490 C2

Authors

Slesarev Vladimir

Dimitrov Todor

Dates

2009-08-10Published

2004-03-31Filed