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2 366 661

(13)

(51)

IPC

C07H19/00(2006-01-01)

C07H19/06(2006-01-01)

C07H19/10(2006-01-01)

A61K31/7064(2006-01-01)

A61P31/12(2006-01-01)

(21) (22)

Application

2005102013/04, 2003-06-27

(24)

Start date

2003-06-27

(22)

Actual filing date

2003-06-27

(45)

Published

2009-09-10

(72)

Inventor

Sommadossi Zhan-P'ErLa Kolla PaoloStorer RichardGosselin Zhil'

(73)

Holder

Ajdeniks LimitedUniversita Del'I Studi Di Kal'JariSantr Nas'Onal' De Lja Reshersh S'Entifik

PROMEDICINES OF MODIFIED 2'- AND 3'-NUCLEOSIDES FOR TREATMENT OF FLAVIVIRIDAE INFECTIONS Russian patent published in 2009 - IPC C07H19/00 C07H19/06 C07H19/10 A61K31/7064 A61P31/12

Abstract RU 2366661 C2

FIELD: medicine.

SUBSTANCE: invention refers to new compounds of formula (IX) or to their pharmaceutically acceptable salts having inhibitory activity to hepatitis C, to the related pharmaceutical composition and to their application for making a medical product. In compound of formula (IX) , R¹ and R² independently represent H, phosphate or acyl; X represents O; base* represents pyrimidine base; R¹² represents C(Y³)₃; Y³ represents H and R¹³ represents fluorine.

EFFECT: higher efficiency of the composition and treatment method.

31 cl, 14 dwg, 26 ex

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RU 2 366 661 C2

Authors

Sommadossi Zhan-P'Er

La Kolla Paolo

Storer Richard

Gosselin Zhil'

Dates

2009-09-10—Published

2003-06-27—Filed