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(19)

(11)

2 437 892

(13)

(51)

IPC

C07H19/20(2006-01-01)

A61K31/7052(2006-01-01)

A61P31/14(2006-01-01)

(21) (22)

Application

2009117156/04, 2003-06-27

(24)

Start date

2003-06-27

(22)

Actual filing date

2003-06-27

(45)

Published

2011-12-27

(72)

Inventor

Sommadossi Zhan-P'ErLa Kolla PaoloStorer RichardGosselin Zhil'

(73)

Holder

Ajdeniks LimitedUniversita Del'I Studi Di Kal'JariSantr Nas'Onal' De Lja Reshersh S'Entifik

MODIFIED 2- AND 3-NUCLEOSIDES AND USE THEREOF TO PRODUCE MEDICINAL AGENT, HAVING HEPATITIS C INHIBITING ACTIVITY Russian patent published in 2011 - IPC C07H19/20 A61K31/7052 A61P31/14

Abstract RU 2437892 C2

FIELD: chemistry.

SUBSTANCE: invention relates to novel compounds of formula or pharmaceutically acceptable salts thereof, having hepatitis C inhibiting activity, pharmaceutical composition based on said compounds and use thereof to produce a medicinal agent. In compounds of formula (IX) R¹ and R² independently denote H, phosphate or acyl; X denotes O; the base* is a purine base; R¹² denotes C(Y³)₃; Y³ denotes H and R¹³ denotes fluorine.

EFFECT: improved properties of the compound.

30 cl, 4 dwg, 26 ex

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RU 2 437 892 C2

Authors

Sommadossi Zhan-P'Er

La Kolla Paolo

Storer Richard

Gosselin Zhil'

Dates

2011-12-27—Published

2003-06-27—Filed