FIELD: medicine.
SUBSTANCE: invention covers phosphinic acid derivatives of formula I which can be used for treating Alzheimer's disease, and methods for making thereof. 
where R1 stands for aryl or heteroaryl; R2 stands for alkyl or phenyl; R3 stands for hydrogen, alkyl or phenyl; R4 stands for alkyl, cycloalkyl, phenyl, pyridyl, tolyl, trifluorobutyl, tetrafluorobutyl, heptafluorobutyl, hydroxyphenyl, methoxyphenyl, methylpyridinyl.
EFFECT: production of new biologically active substances.
11 cl, 6 ex
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