CRYSTALLINE FORM OF QUINOLIN COMPOUND AND METHOD OF OBTAINMENT OF COMPOUND IN GIVEN FORM Russian patent published in 2009 - IPC C07D215/14 A61K31/47 A61P3/06 

Abstract RU 2370489 C2

FIELD: pharmacology.

SUBSTANCE: invention concerns novel crystal (crystal form A) of compound of the formula (1): , containing 5 to 15% of water and demonstrates peak at relative intensity of over 25% and diffraction angle (2θ) of 30.16° by powder X-ray diffraction measured using CuK α-radiation. Additionally invention concerns method of obtaining crystal (crystal form A) from cl.1, method of obtaining therapeutic substance of crystal (crystal form A) from cl.1, and pharmaceutical composition.

EFFECT: obtaining novel bioactive compound showing HMG-CoA reductase inhibition effect.

4 cl, 1 ex, 1 tbl

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RU 2 370 489 C2

Authors

Okhara Josio

Takada Jasutaka

Matsumoto Khiroo

Josida Akikhiro

Dates

2009-10-20Published

2004-12-17Filed