COCRYSTALLINE FORM OF C-GLYCOSIDE DERIVATIVE WITH L-PROLIN Russian patent published in 2011 - IPC C07D407/10 C07D409/10 A61K31/381 A61P3/10 

Abstract RU 2408595 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: this invention relates to cocrystalline form of (1S)-1,5-anhydro-1-[3-(1-benzothiene-2-ylmethyl)-4-fluorophenyl]-D-glucitol (compound A) with L-proline. Proposed cocrystalline form is a promising anti-diabetes medicine.

EFFECT: cocrystalline form of compound is characterised with constant composition, improved stability in storage, and also low hygroscopicity, and is suitable for use as crystalline medicinal substance to produce pharmaceutical preparations.

11 cl, 1 ex, 2 tbl, 10 dwg

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RU 2 408 595 C2

Authors

Imamura Masakazu

Nakanisi Kejta

Siraki Riota

Onda Keniti

Sasuga Dajsuke

Juda Masamiti

Dates

2011-01-10Published

2007-04-04Filed