CRYSTAL OF AZOLE BENZENE DERIVATIVE Russian patent published in 2018 - IPC C07D417/10 A61K31/427 A61P1/04 A61P3/06 A61P3/10 A61P9/00 A61P9/10 A61P9/12 A61P11/00 A61P13/02 A61P13/04 A61P13/12 A61P19/06 A61P35/00 A61P37/06 A61P43/00 

FIELD: chemistry.

SUBSTANCE: invention relates to a crystal of 2-[4-(2,2-dimethylpropoxy)-3-(1H-1,2,3,4-tetrazol-1-yl)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid (crystalline form A), characterised by at least one of (I)–(III): (I) its powder X-ray diffraction spectrum has characteristic peaks with diffraction angles 2θ(±0.5 °)=7.2 °, 11.3 °, 15.9 °, 17.9 °, 20.8 °, 22.3 °, 23.1 °, 23.8 °, 24.3 ° and 28.6 °; (II) its powder X-ray diffraction spectrum has the structure depicted in fig. 1; or (III) its exothermic peak in thermogravimetry/differential thermal analysis is at 232 °C ±5 °C.

EFFECT: compound of the invention has the properties of xanthine oxidase inhibitor and is intended for use as a therapeutic or prophylactic agent for diseases associated with xanthine oxidase.

4 cl, 1 dwg, 2 tbl, 8 ex