DIFFERENTIAL DIAGNOSTIC TECHNIQUE FOR TUMOURS FROM PERIPHERAL NERVE SHEATHS Russian patent published in 2009 - IPC A61B10/00 A61B10/02 G01N1/28 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to oncology, pathomorphology. Differential diagnostics of tumours from peripheral nerve sheaths is ensured by analysing the results of excised soft tissue tumour morphology. At first, a neoplasm is considered to belong to tumours from nerve sheaths by specified criteria, and then differential diagnosis between nosologic forms making the given group follows. Values related with morphological signs, as tumour size, surrounding tissues border, tumour composition, histological pattern, cell morphology, malignance signs, axon presence, tumour stroma, secondary changes and immunohistochemical cell profile are specified and summarised. The greater amount of any given value indicate the diagnosis: A - neurofibroma, B - neuroschwannoma, C - perineurinoma, D - malignant tumour from peripheral nerve sheaths, A=B - hybrid neurofibroma and neuroschwannoma, A=C - hybrid neurofibroma and perineurinoma, B=C - hybrid neuroschwannoma and perineurinoma.

EFFECT: method improves diagnostic accuracy of tumours from peripheral nerve sheaths and ensures reduced time required for pathomorphological resolution due to detailed task-specific morphology of neoplasm characteristics.

3 dwg, 3 ex, 3 tbl