COMBINATION THERAPY OF LOCALLY ADVANCED NON-SMALL CELL LUNG CANCER Russian patent published in 2009 - IPC A61K31/337 A61K31/282 A61K31/7068 A61P35/00 A61N5/10 

Abstract RU 2372901 C2

FIELD: medicine.

SUBSTANCE: invention relates to medicine area, namely to oncology, and can be used for treatment of locally advanced non-small cell lung cancer. The therapy involves neoadjuvant chemotherapy, introduction of a radio sensitiser, surgical treatment and intraoperative radiation therapy. The preoperative period involves 2 courses of neoadjuvant chemotherapy with Taxol and carboplatin. Two hours before irradiation, gemcitabine is introduced in a dose 300 mg/m2, then radical operation with intraoperative radiation therapy in a single dose 15 Gy on regional lymphatic cancer spread area is performed.

EFFECT: invention allows improving clinical effectiveness of locally advanced non-small cell lung cancer owing to reduced post-radiation complications and higher survival rate of patients.

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Authors

Dobrodeev Aleksej Jur'Evich

Zav'Jalov Aleksandr Aleksandrovich

Tuzikov Sergej Aleksandrovich

Musabaeva Ljudmila Ivanovna

Miller Sergej Viktorovich

Dates

2009-11-20Published

2007-04-24Filed