FIELD: medicine.
SUBSTANCE: invention relates to medicine area, namely to oncology, and can be used for treatment of locally advanced non-small cell lung cancer. The therapy involves neoadjuvant chemotherapy, introduction of a radio sensitiser, surgical treatment and intraoperative radiation therapy. The preoperative period involves 2 courses of neoadjuvant chemotherapy with Taxol and carboplatin. Two hours before irradiation, gemcitabine is introduced in a dose 300 mg/m2, then radical operation with intraoperative radiation therapy in a single dose 15 Gy on regional lymphatic cancer spread area is performed.
EFFECT: invention allows improving clinical effectiveness of locally advanced non-small cell lung cancer owing to reduced post-radiation complications and higher survival rate of patients.
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Authors
Dates
2009-11-20—Published
2007-04-24—Filed