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2 455 986

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IPC

A61K31/282(2006-01-01)

A61K31/475(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2011105847/15, 2011-02-16

(24)

Start date

2011-02-16

(22)

Actual filing date

2011-02-16

(45)

Published

2012-07-20

(72)

Inventor

Polishchuk Tat'Jana VladimirovnaMiller Sergej ViktorovichTuzikov Sergej AleksandrovichGol'Dberg Viktor Evgen'EvichJumov Evgenij Leonidovich

(73)

Holder

Uchrezhdenie Rossijskoj Akademii Meditsinskikh Nauk Nauchno-Issledovatel'Skij Institut Onkologii Sibirskogo Otdelenija Rossijskoj Akademii Meditsinskikh Nauk Onkologii So Ramn)

METHOD OF COMBINED TREATMENT OF NON-SMALL CELL LUNG CANCER OF II AND III STAGE Russian patent published in 2012 - IPC A61K31/282 A61K31/475 A61P35/00

Abstract RU 2455986 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to medicine, namely to oncology, and deals with method of combined treatment of non-small cell lung cancer of II and III stage. Method includes 2 courses of neoadjuvant chemotherapy with application of carboplatin and further radical surgery. Neoadjuvant therapy is carried out by intravenous introduction of vinorelbine in dose 25 mg/ m² on 1 and 8 days of cycle, on the second day, 20 hours after introduction of vinorelbine carboplatin is introduced intravenously by drop infusion in dose by AUG 6, interval between courses of chemotherapy constitutes 20 days. After that in post-operative period on 14 day additionally carried out is adjuvant chemotherapy in the same regimen, with number of course being 3-4.

EFFECT: invention ensures increased efficiency of treatment of non-small cell lung cancer of II and III stage due to reduction of complications and increase of patients' survival.

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RU 2 455 986 C1

Authors

Polishchuk Tat'Jana Vladimirovna

Miller Sergej Viktorovich

Tuzikov Sergej Aleksandrovich

Gol'Dberg Viktor Evgen'Evich

Jumov Evgenij Leonidovich

Dates

2012-07-20—Published

2011-02-16—Filed