FIELD: chemistry; biochemistry.
SUBSTANCE: invention relates to biotechnology, specifically to production of new cell lines, and can be used for making anti-tumour vaccines. A novel human melanoma cell line mel Gus is disclosed, which has stable cultural and morphological characteristics and is stored in the Special collection of cell cultures of the Institute of Cytology RAS under number RKKK (P) 707D. The obtained cell line is characterised by expression of melanoma (differentiation) markers - CD63, HMW, MelanA, HMB45, as well as cancerous-testicular marker MAGE-3, presence of first and second class histocompatibility antigens.
EFFECT: increased effectiveness of anti-tumour (whole cell, genetically engineered) vaccines, used for treating melanoma and other malignant growths.
1 tbl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| CELL LINE OF HUMAN MELANOMA mel H, APPLIED FOR OBTAINING ANTITUMOUR VACCINE | 2009 |
|
RU2402604C1 |
| HUMAN MELANOMA CELL LINES mel Si, USED FOR MAKING TUMOUR VACCINE | 2008 |
|
RU2363734C1 |
| CELL LINE OF HUMAN MELANOMA mel Rac, APPLIED FOR OBTAINING ANTITUMOUR VACCINE | 2009 |
|
RU2402602C1 |
| CELL LINE OF HUMAN MELANOMA mel Mtp USED FOR MAKING ANTICANCER VACCINES | 2008 |
|
RU2360963C1 |
| CELL LINE OF HUMAN MELANOMA mel Cher, USED FOR OBTAINING ANTI-TUMOR VACCINES | 2008 |
|
RU2364624C1 |
| HUMAN MELANOMA CELL LINE mel Ch, USED FOR MAKING ANTI-TUMOUR VACCINES | 2008 |
|
RU2373279C1 |
| CELL LINE OF HUMAN MELANOMA mel Me, APPLIED FOR OBTAINING ANTITUMOUR VACCINE | 2009 |
|
RU2402603C1 |
| HUMAN MELANOMA CELLULAR LINE mel Kor USED IN PREPARING ANTITUMOR VACCINE | 2005 |
|
RU2287578C1 |
| HUMAN MELANOMA CELLULAR LINE mel IL USED IN PREPARING ANTITUMOR VACCINE | 2005 |
|
RU2287577C1 |
| HUMAN MELANOMA CELLULAR LINE mel Ibr USED IN PREPARING ANTITUMOR VACCINE | 2005 |
|
RU2287576C1 |
