NEW WATER-SOLUBLE FORM OF COENZYME Q10 REPRESENTING INCORPORATION COMPLEX WITH BETA-CYCLODEXTRINE, METHOD FOR MAKING AND APPLICATION THEREOF Russian patent published in 2009 - IPC A61K31/122 A61K47/40 

Abstract RU 2375053 C2

FIELD: medicine.

SUBSTANCE: invention refers to pharmaceutical, cosmetic and food industries, and represents method for making a water-soluble form of coenzyme Q10 representing an incorporation complex of β-cyclodextrine with coenzyme Q10 wherein molar ratio of β-cyclodextrine and coenzyme Q10 makes approximately 1:1, differing that β-cyclodextrine is dissolved in water at temperature 30°C to boiling temperature, preferentially 55°C to boiling temperature, then solid coenzyme Q10 is with continuing agitation at temperature 60-70°C, and then at room temperature.

EFFECT: higher water-solubility of said water-soluble form, improved biological digestibility and efficiency.

8 cl, 5 ex, 7 tbl, 5 dwg

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RU 2 375 053 C2

Authors

Proshek Mirko

Shmidovnik Andrej

Fir Maja

Strazhishar Monika

Gol'Ts Vondra Alenka

Andrenshek Samo

Zhmitek Janko

Dates

2009-12-10Published

2005-05-10Filed