APPLICATION OF TIMOSAPONIN B-II IN MAKING DRUG OR PRODUCT FOR STROKE PREVENTION AND TREATMENT Russian patent published in 2009 - IPC A61K31/58 A61P9/10 

Abstract RU 2376993 C2

FIELD: medicine.

SUBSTANCE: there is offered application of timosaponin B-II (25S)-26-O-β-D-glucopyranosyl-22-hydroxy-5β-furostan-3β,26-dyol-3-O-β-D-glucopyranosyl(1→2)-β-D-galactopyranosidee, the very same prototimosaponin A-III a basic component of Anemarrhenae, optionally of purity ≥90% in making a drug for stroke (apoplexy) prevention or treatment.

EFFECT: timosaponin BII known previously for elimination of 57% of free radicals, relieves neurologic symptoms in rats with cerebral ischemia, reduces extension of cerebral infarction, cerebral oedema, inflammatory damage in cerebral ischemia, improves hemorheology (reduces blood viscosity and aggregation of erythrocytes, increases deformation capacity thereof).

2 cl, 5 tbl, 3 ex

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RU 2 376 993 C2

Authors

Ma Bajpin

Sjuj Tsjupin

Chzhao Jan

Sjun Chehntsi

Tan Davehj

Dates

2009-12-27Published

2005-04-21Filed